In the rapidly evolving industry of professional skincare, innovation is everything. High-performance ingredients that support cellular regeneration and skin recovery have garnered significant attention from consumers. Among these, three breakthrough ingredients have risen to prominence among skincare professionals and formulators: NAD⁺ (Nicotinamide Adenine Dinucleotide), Exosomes, and PDRN (Polydeoxyribonucleotide).
These ingredients are behind some of the most advanced skin treatments today. Once reserved for medical or regenerative treatments, they are now making waves in aesthetic skincare. And while they sound scientific, their benefits are simple: healthier, younger-looking skin.
NAD⁺ – Cellular Energy for Your Skin
NAD⁺ (Nicotinamide Adenine Dinucleotide) is something your body naturally makes. It’s a coenzyme and molecule that helps your cells produce energy, repair damage, and stay healthy. As you age, NAD⁺ levels drop, which slows down skin renewal and leads to dullness, fine lines, dryness, and increased risks of inflammatory skin conditions.

Even though NAD⁺ isn’t as well-known yet in skincare, it’s getting noticed fast—especially in Korea. Why? Because it helps boost how your skin responds to other ingredients, supports the skin’s natural repair system, and can even help improve elasticity and tone over time.
By enhancing cellular energy production and activating repair pathways, NAD⁺ improves skin resilience and optimizes the efficacy of complementary active ingredients, contributing to improvements in texture, firmness, and radiance.
PDRN – The Skin Rebuilder
PDRN (Polydeoxyribonucleotide) is derived from salmon DNA and is recognized in Korean dermatology for its remarkable regenerative properties. Its DNA component is similar to human skin tissue.
PDRN is especially effective for skin recovery after clinical treatments such as laser therapy and micro-needling. It helps reduce inflammation, strengthen the skin barrier, and improve overall skin texture, making it a popular ingredient in post-procedure care and anti-aging products.
When combined with NAD⁺, PDRN offers complementary benefits — enhancing both cellular metabolism and strengthening the skin’s structural foundation—resulting in comprehensive skin renewal.
Exosomes – Extracellular Messengers
Exosomes are tiny extracellular vesicles extracted from plants that facilitate communication between cells by transporting proteins, lipids, and genetic material. In skincare, plant-derived exosomes have been popular for their ability to stimulate skin regeneration and modulate inflammatory responses.
What makes Exosomes special? They tell your skin to regenerate—to heal, calm, and strengthen.
i Fill Ceuti-Shot: NAD+, PDRN, and Exosomes — All in One

The i Fill Ceuti-Shot is a professional-grade product formulated to combine the power of NAD⁺, PDRN, and plant-derived Exosomes with an innovative delivery technology to maximize skin absorption and efficacy.
Using the Induced Fill Technology to deliver the power of the patented Dissolving Micro Ceuti-Shot (DMS), which employs over 3,100 microscopic Hyaluronic Acid complexes, micro-hydration channels are created in the skin’s outer later. This technology enhances the penetration of active ingredients deeper in the dermis, while minimizing irritation and preserving the skin barrier.
Unlike traditional mechanical micro-needling, the micro-hydration channels formed by Dissolving Micro Ceuti-Shot technology allow for safe, comfortable, and highly efficient delivery of active ingredients without causing trauma or downtime.
Multi-Functional NAD⁺ Ampoules with Targeted Benefits

The system features four distinct NAD⁺ ampoules, each formulated with NAD⁺, Salmon-derived PDRN, and a specific plant-derived exosome selected for targeted skin benefits:
– NAD-H Ampoule (Tomato Callus Exosome)
Provides deep hydration, strengthens the skin barrier, and offers antioxidant protection.
– NAD-W Ampoule (Lavender Callus Exosome)
Focuses on wrinkle reduction, improved skin elasticity, and antioxidant defense.
– NAD-O Ampoule (Centella Asiatica Callus Exosome)
Targets pore minimization, texture refinement, and skin firmness.
– NAD-P Ampoule (Ice Plant Callus Exosome)
Enhances skin brightening, detoxification, and complexion clarity.
This four-week program involves sequential weekly use of each ampoule combined with the Ceuti-Shot roller, enabling comprehensive skin renewal through hydration, anti-aging, texture improvement, and brightening.
Clinical Efficacy and Professional Use
i Fill Ceuti-Shot is targeted for professional use only to ensure safe and effective treatment. Its innovative delivery system allows practitioners to achieve significant improvements in skin hydration, elasticity, pore appearance, and overall tone with minimal discomfort and downtime.
For those considering at-home application, professional consultation and supervision are strongly recommended to optimize safety and results.
For more information about i Fill Ceuti-Shot, check out OxygenCeuticals Official Online Store HERE.
For inquires, please contact OxygenCeuticals Official at global@oxyfacial.com
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